Antipsychotic effect of buprenorphine in schizophrenia
- 1 October 1987
- journal article
- research article
- Published by American Psychiatric Association Publishing in American Journal of Psychiatry
- Vol. 144 (10) , 1340-1342
- https://doi.org/10.1176/ajp.144.10.1340
Abstract
The antipsychotic potency of the partial opiate agonist buprenorphine was evaluated in 10 neuroleptic-free schizophrenic patients suffering from frequent hallucinations, delusions, and severe formal thought disorders. Buprenorphine had a pronounced antipsychotic effect, which lasted about 4 hours, in patients with schizophreniform disorders (N=4) and paranoid schizophrenia (N=3).This publication has 6 references indexed in Scilit:
- Dopamine and the action of opiates: A reevaluation of the dopamine hypothesis of schizophrenia with special consideration of the role of endogenous opioids in the pathogenesis of schizophreniaBiological Psychiatry, 1985
- β-Endorphin and SchizophreniaArchives of General Psychiatry, 1980
- Human Pharmacology and Abuse Potential of the Analgesic BuprenorphineArchives of General Psychiatry, 1978
- THE ANIMAL PHARMACOLOGY OF BUPRENORPHINE, AN ORIPAVINE ANALGESIC AGENTBritish Journal of Pharmacology, 1977
- Indication of an Antipsychotic Action of the Opiate Antagonist NaloxonePharmacopsychiatry, 1977
- Increased CSF levels of endorphines in chronic psychosisNeuroscience Letters, 1976