Association between Haptoglobin Groups and Hereditary Predisposition for Bronchial Asthma
- 1 January 1989
- journal article
- research article
- Published by S. Karger AG in Human Heredity
- Vol. 39 (1) , 7-11
- https://doi.org/10.1159/000153824
Abstract
Haptoglobin (Hp) groups were investigated in 148 patients with bronchial asthma. A significant (p < 0.005) deviation from the expected Hardy-Weinberg equilibrium, with a decreased frequency of heterozygotes, was observed among patients with a family history of asthma. This deviation was more pronounced among patients with adult onset of asthma. The presence or absence of atopy had no significant influence on the phenotype distribution.Keywords
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