ULTRASTRUCTURAL-STUDY OF DEGOS DISEASE - REPORT OF A NEW CASE AND LITERATURE-REVIEW

  • 1 January 1977
    • journal article
    • review article
    • Vol. 104  (4) , 280-293
Abstract
An observation of a new case of Degos'' disease in a 42 yr old woman presenting only cutaneous symptoms permitted a detailed ultrastructural study of vascular lesions, nerves, infiltrates and perivascular fibroblasts. The episodic clinical evolution with various formation periods of vascular lesions, the frequency of virus-like inclusions in the endothelial cells and fibroblasts, as well as C3 [complement component 3] deposits and the presence of intracytoplasmic cylinders in the histiocytes, suggest a physiopathologic mechanism common to autoimmune diseases. A bibliographic review accompanies the clinico-pathological study.