Fetal and Postnatal Development of the Adrenal Glands in Macaca mulatta1

Abstract
To examine the role of FSH during follicular maturation in monkeys, serum FSH was suppressed during cycles on Days 1-4 i.p. by administration of charcoal-treated porcine follicular fluid (PFFl, crude inhibin-F). Following PFFl treatment, the putative dominant follicle was examined on Days 10-14. Granulosa cells were recovered from this follicle and cultured. Treatment of four monkeys with PFFl led to decreased size of the dominant follicle and a decrease in the number of granulosa cells recovered from the follicle. Serum FSH, but not LH, levels were decreased 50-80% in three of four monkeys. Pig serum (control) had no discernible effects.