Platelet Collection with the Autopheresis-C® Apheresis System

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Abstract
This report describes a new system for collection of platelet concentrate (PC) and cell-free plasma (PPP) from apheresis donors. The system uses two separation devices and requires only a single venipuncture. The Plateletcell device separates the PPC into PC and PPP. Results of functional studies performed indicate that the separation process does not alter viability of either the PPC, the PC, or the PPP. Platelet function after 5 days of storage is maintained. An average yield of 3.4 .+-. 1011 platelets in 201 g of PC and 422 g of PPP were harvested in 71 .+-. 13 min of donor time from donors with preprocedure hematocrits averaging 42.5 .+-. 2.0% and preprocedure platelet counts averaging 265 .+-. 61 .times. 103/.mu.l.