Sparing Action of Protein on the Pantothenic Acid Requirement of the Rat.

Abstract
Studies on the pantothenic acid requirement of the rat were carried out with diets varying in their proportion of carbohydrate and protein. Rats maintained on a pantothenic acid deficient diet containing 64% casein grew more and survived much longer than littermates on a 24% casein deficient diet under the same conditions. This occurred both when the deficiency was instituted at birth and when it was instituted at weaning. Several possible explanations for this sparing action of high-casein diets are given.