Abstract
METASTATIC Tumors of the central nervous system are not uncommon; their diagnosis is often difficult, and the pertinent literature, as Globus1commented, is relatively meager. It therefore was thought worthy of interest to review the material in the laboratory of neuropathology of the Philadelphia General Hospital. These cases are drawn not only from the neurologic and neurosurgical wards but from the medical, surgical and radiologic services as well. The cases of metastatic involvement of the central nervous system have been grouped on the following basis. Group 1. —Forty-two cases in which the metastatic involvement apart from extension to the regional lymph nodes, was observed only in the brain in the form of discrete metastatic nodules, either single or multiple, ranging in size from 1 to 9 cm. In this group the clinical signs and symptoms simulated those of a primary intracerebral lesion. Group 2. —Sixty-seven cases in which the

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