Cellular studies of auditory hair cell regeneration in birds
- 24 October 2000
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 97 (22) , 11714-11721
- https://doi.org/10.1073/pnas.97.22.11714
Abstract
A decade ago it was discovered that mature birds are able to regenerate hair cells, the receptors for auditory perception. This surprising finding generated hope in the field of auditory neuroscience that new hair cells someday may be coaxed to form in another class of warm-blooded vertebrates, mammals. We have made considerable progress toward understanding some cellular and molecular events that lead to hair cell regeneration in birds. This review discusses our current understanding of avian hair cell regeneration, with some comparisons to other vertebrate classes and other regenerative systems.Keywords
This publication has 140 references indexed in Scilit:
- Neuronal regeneration: Lessons from the olfactory systemSeminars in Cell & Developmental Biology, 1999
- Evidence for supporting cell proliferation and hair cell differentiation in the basilar papilla of adult Belgian Waterslager canaries (Serinus canarius)Journal of Comparative Neurology, 1997
- Control of Daughter Cell Fates during Asymmetric Division: Interaction of Numb and NotchNeuron, 1996
- Numb Antagonizes Notch Signaling to Specify Sibling Neuron Cell FatesNeuron, 1996
- Post-Traumatic Survival and Recovery of the Auditory Sensory Cells in CultureActa Oto-Laryngologica, 1996
- Dynamics of MASH1 Expression in Vitro and in Vivo Suggest a Non-Stem Cell Site of MASH1 Action in the Olfactory Receptor Neuron LineageMolecular and Cellular Neuroscience, 1995
- Supporting cells in isolated sensory epithelia of avian utricles proliferate in serum-free cultureNeuroReport, 1995
- Genesis of olfactory receptor neurons in vitro: Regulation of progenitor cell divisions by fibroblast growth factorsNeuron, 1994
- Evidence for supporting cell mitosis in response to acoustic trauma in the avian inner earJournal of Neurocytology, 1992
- The role of macrophages in the disposal of degeneration products within the organ of corti after acoustic overstimulationActa Oto-Laryngologica, 1990