Clinical Relevance of Activity Parameters in Crohn’s Disease Estimated by the Faecal Excretion of 111In-Labeled Granulocytes
- 1 January 1991
- journal article
- research article
- Published by S. Karger AG in Digestion
- Vol. 50 (3-4) , 149-152
- https://doi.org/10.1159/000200755
Abstract
The fecal excretion of 111In -oxine-labeled autologous granulocytes was determined in 58 patients with Crohn’s disease. A representative analysis of the total amount of excreted cells requires a 4-day stool sampling at least in those patients suffering from Crohn’s ileitis or ileocolitis. Various laboratory tests (Orosomucoid, α1-antitrypsin, C-reactive protein, erythrocyte sedimentation rate, leukocytes, thrombocytes, albumin, Fe, α1-globulin and α2-globulin) and the van Hees index significantly correlated with this specific estimate of intestinal inflammation, indicating that it is of little importance which one is clinically used for the assessment of inflammatory activity in Crohn’s disease.Keywords
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