Stereocontrolled synthesis of pseudo C2-symmetric 1,3-diamino-2-propanol core units of HIV protease inhibitors
- 20 January 1997
- journal article
- Published by Elsevier in Tetrahedron Letters
- Vol. 38 (3) , 499-502
- https://doi.org/10.1016/s0040-4039(96)02355-6
Abstract
No abstract availableThis publication has 11 references indexed in Scilit:
- Thiazole-Based Stereoselective Routes to Leucine and Phenylalanine Hydroxyethylene Dipeptide Isostere Inhibitors of Renin and HIV-1 Aspartic ProteaseThe Journal of Organic Chemistry, 1995
- Chelation- and Non-chelation-Controlled Addition of 2-(Trimethylsilyl)thiazole to .alpha.-Amino Aldehydes: Stereoselective Synthesis of the .beta.-Amino-.alpha.-hydroxy Aldehyde Intermediate for the Preparation of the Human Immunodeficiency Virus Proteinase Inhibitor Ro 31-8959The Journal of Organic Chemistry, 1995
- Stereoselective Homologation–Amination of Aldehydes by Addition of Their Nitrones to C‐2 Metalated Thiazoles—A General Entry to α‐Amino Aldehydes and Amino SugarsChemistry – A European Journal, 1995
- Total Synthesis of (+)-Galactostatin. An Illustration of the Utility of the Thiazole-Aldehyde SynthesisThe Journal of Organic Chemistry, 1995
- Diastereo‐ and Enantioselective Synthesis of C2‐Symmetrical HIV‐1 Protease InhibitorsAngewandte Chemie International Edition in English, 1993
- A diastereoselective synthesis of pseudo-C2 -symmetric 1,3-diamino-2-propanols as core units in HIV protease inhibitorsTetrahedron, 1993
- 2-Thiazolyl α-Amino Ketones: A New Class of Reactive Intermediates for the Stereocontrolled Synthesis of Unusual Amino AcidsSynthesis, 1993
- Stereocontrolled synthesis of C2-symmetric and pseudo-C2-symmetric diamino alcohols and diols for use in HIV protease inhibitorsThe Journal of Organic Chemistry, 1992
- Structure-based, C2 symmetric inhibitors of HIV proteaseJournal of Medicinal Chemistry, 1990
- Design, Activity, and 2.8 Å Crystal Structure of a C 2 Symmetric Inhibitor Complexed to HIV-1 ProteaseScience, 1990