Effect of L-thyroxine on gastric secretion in the pylorus-ligated rat.

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Abstract
L-thyroxine inhibits gastric secretion initially, as does dessicated thyroid, but after 8-9 weeks of administration every other day, secretion returns to normal. Vagal control is believed not to be affected; it is suggested that the adrenal cortical hypertrophy which occurs is associated with hypofunction of the adrenal cortex.