A genetically engineered human IgG with limited flexibility fully initiates cytolysis via complement
Open Access
- 1 April 1993
- journal article
- Published by Elsevier in Molecular Immunology
- Vol. 30 (6) , 603-609
- https://doi.org/10.1016/0161-5890(93)90035-a
Abstract
No abstract availableKeywords
This publication has 21 references indexed in Scilit:
- Effect of light chain V region duplication on IgG oligomerization and in vivo efficacyScience, 1991
- Antibody–antigen flexibilityNature, 1987
- Is IgM-like dislocation a common feature of antibody function?Immunology Today, 1986
- Immunoglobulin flexibility in complement activationImmunology Today, 1986
- Unpaired cysteine-54 interferes with the ability of an engineered disulfide to stabilize T4 lysozymeBiochemistry, 1986
- EFFECTS OF SITE-SPECIFIC AMINO ACID MODIFICATION ON PROTEIN INTERACTIONS AND BIOLOGICAL FUNCTIONAnnual Review of Biochemistry, 1985
- Segmental flexibility of immunoglobulin G antibody molecules in solution: a new interpretationBiochemistry, 1981
- Crystallographic refinement and atomic models of the intact immunoglobulin molecule Kol and its antigen-binding fragment at 3.0 Å and 1.9 Å resolutionJournal of Molecular Biology, 1980
- Structure of the human antibody molecule kol (immunoglobulin G1): An electron density map at 5 Å resolutionJournal of Molecular Biology, 1976
- Segmental flexibility in an antibody moleculeJournal of Molecular Biology, 1970