Role of Intestinal Bacteria in Aromatization of Quinic Acid in Man and Guinea Pig.
- 1 July 1960
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 104 (3) , 424-426
- https://doi.org/10.3181/00379727-104-25860
Abstract
When quinic acid is given orally to men and to guinea pigs, it is aromatized and appears in the urine as hippuric acid. Neomycin, in doses sufficient to inhibit bacterial multiplication in the intestinal tract, prevents the conversion of quinic to hippuric acid in man. When quinic acid is given parenterally to guinea pigs, it is not converted to hippuric acid. It is concluded that aromatization of quinic acid in man and in the guinea pig is achieved by intestinal bacteria.Keywords
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