Changes in the nuclear-plasmic ratio of mammals during hunger

Publisher Website
Google Scholar
Abstract
The chemical nuclear-cytoplasmic ratio of liver and of skeletal muscles, from the beginning stages of inanition to the pre-mortal rise of N excretion, has been traced in rabbits. The purine-N of skeletal muscle had an average of 104.6 mgm.%; it varied from 85 to 119 mgm.%. Nucleo-cytoplasmic ratio was 28.55X103. Both this ratio and the purine-N remained constant. The purine-N of the liver varied from 149.5 mgm.% in fed animals to 162.1 mgm.% in inanition. The mean nucleo-cytoplasmic ratio was 50.9X103 before starvation; after starvation, 48.4X 103. Over 50% of the muscle purines were extracted by hot water and therefore were not contained in the nucleus. Parallel nucleo-cytoplasmic ratios were obtained on muscle from which purines had been removed by hot water. The agreement between change of nuclein-P content and of purine-N content observed by some workers is probably due to the relatively constant content of extranuclear purines in tissues.

This publication has 2 references indexed in Scilit: