Immunological relatedness of glucose 6-phosphate dehydrogenases from vertebrate and invertebrate species.

Publisher Website
Google Scholar
Abstract
Rabbit antisera against crucian carp glucose 6-phosphate dehydrogenase were prepared and their relative inhibition potencies were examined against glucose 6-phosphate dehydrogenases from 23 spp. of teleosts, 5 spp. of other vertebrates and 8 spp. of invertebrates. The immunological relatedness of teleosts expressed as the relative inhibition potencies of antibody against the enzymes is consistent with the phyletic relationships of teleosts depicted by Greenwood et al.; i.e., the inhibition potencies were: carp, 0.78; dace, 0.69; loaches, 0.38; 3 spp. of Salmoniformes, 0.19; eels 0.08. The inhibition potencies of vertebrates other than teleosts and of invertebrates ranged from 0.0008-0.0012, and 0-0.0004, respectively. Ascarid and planarian enzymes were not inhibited by any antiserum tested. Electrophoretic examination of the mixture of these enzymes and antibody revealed that the enzymes possess at least 1 antigenic determinant common to crucian carp enzyme. No immunological similarity was found between yeast and crucian carp glucose 6-phosphate dehydrogenases and between glucose 6-phosphate dehydrogenase and hexose 6-phosphate dehydrogenase of crucian carp.

This publication has 0 references indexed in Scilit: