Liquid Membrane Electrodes for the Potentiometric Determination of Scopolamine Hydrobromide and N-Butyl Scopolammonium Bromide

Abstract
Liquid-membrane electrodes sensitive to scopolamine+ and N-butyl scopolammonium+ are described for the direct or indirect assay of scopolamine hydrobromide and N-butyl scopolammoniumbromide, respectively, in pharmaceutical preparations. All electrodes exhibit a linear response to respective organic cation over the range of lo−1 to lo−4 M. No interference from the common imgredient substances was observed.