A Facile 1,3-Dipolar Cycloaddition of Nitrile Oxides to Chlorocarbonyl Isocyanate: Synthesis of 4-Chlorocarbonyl-5-oxo-4,5-dihydro-1,2,4-oxadiazoles
- 1 January 1988
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1988 (12) , 994-995
- https://doi.org/10.1055/s-1988-27781
Abstract
The 1,3-dipolar cycloaddition of substituted benzonitrile oxides to the C=N group of chlorocarbonyl isocyanate in chloroform gives potentially useful 3-aryl-4-chlorocarbonyl-5-oxo-4,5-dihydro-1,2,4-oxadiazoles in 75-80% yields.Keywords
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