Secular changes in thyroid uptake

Abstract
It may be of interest to compare the changes in the normal range of thyroidal radioiodine uptake as reported by Kirkman (1974) with those we have reported (Keeling and Williams, 1972). The main feature is the similarity of the findings: a “drift” of the average uptake in a group of euthyroid subjects to lower values over the last (approximately) decade and a half, with latterly a reduction in the magnitude of the change. In both Kirkman's and our studies the results suggested that a small reduction was continuing but in neither series were the recent results significantly different from those obtained in the middle to later 1960s.

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