Depletion of Phosphatidylinositol 4,5-Bisphosphate by Activation of Phospholipase C-coupled Receptors Causes Slow Inhibition but Not Desensitization of G Protein-gated Inward Rectifier K+ Current in Atrial Myocytes
Open Access
- 1 February 2001
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 276 (8) , 5650-5658
- https://doi.org/10.1074/jbc.m009179200
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- Phosphatidylinositol 4,5-Bisphosphate Is Acting as a Signal Molecule in α1-Adrenergic Pathway via the Modulation of Acetylcholine-activated K+ Channels in Mouse Atrial MyocytesPublished by Elsevier ,2001
- Novel Inhibition of Gβγ-activated Potassium Currents Induced by M2 Muscarinic Receptors via a Pertussis Toxin-insensitive PathwayJournal of Biological Chemistry, 2000
- Synergistic Activation of G Protein–Gated Inwardly Rectifying Potassium Channels by the βγ Subunits of G Proteins and Na+ and Mg2+ IonsThe Journal of general physiology, 1999
- Antisense oligonucleotides against receptor kinase GRK2 disrupt target selectivity of β‐adrenergic receptors in atrial myocytesFEBS Letters, 1999
- DESENSITIZATION OF G-PROTEIN–COUPLED RECEPTORS IN THE CARDIOVASCULAR SYSTEMAnnual Review of Physiology, 1999
- Isoprenaline can activate the acetylcholine‐induced K+ current in canine atrial myocytes via Gs‐derived βγ subunitsThe Journal of Physiology, 1999
- PIP 2 and PIP as Determinants for ATP Inhibition of K ATP ChannelsScience, 1998
- G PROTEIN–COUPLED RECEPTOR KINASESAnnual Review of Biochemistry, 1998
- ATP‐dependent desensitization of the muscarinic K+ channel in rat atrial cellsThe Journal of Physiology, 1997
- In vivodownregulation of M2receptors revealed by measurement of muscarinic K+current in cultured guinea-pig atrial myocytesThe Journal of Physiology, 1997