Multiple structural genes for the ? chain of canine (Canis familiaris) hemoglobin

Abstract
There are two forms of the α chain of canine hemoglobin differing only at residue 130. One form (Tα) contains threonine at this position, the other (Aα) contains alanine. Studies of two Labrador dog families strongly support the existence of multiple α-chain structural genes as the basis of the α-chain heterogeneity. There must be at least one gene locus forTα and one forAα; the exact number of loci has not been determined. Two other dog breeds, the Basenji and the Beagle, also have bothTα and Aα chains.

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