Sedative and anticonvulsant activities of goodyerin, a flavonol glycoside from Goodyera schlechtendaliana
- 15 May 2002
- journal article
- research article
- Published by Wiley in Phytotherapy Research
- Vol. 16 (3) , 261-263
- https://doi.org/10.1002/ptr.862
Abstract
Goodyerin is a flavonol glycoside isolated from the whole plants of Goodyera schlechtendaliana which has been used as a substitute for the crude drug, Anoectochilus formosanus. The pharmacological properties of goodyerin were assayed for effects on spontaneous locomotor activity, on pentobarbital-induced hypnosis, and on anticonvulsant activity against picrotoxin-induced seizures in rodents. Goodyerin exhibited a significant and dose-dependent sedative and anticonvulsant effect. Copyright © 2002 John Wiley & Sons, Ltd.Keywords
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