Antibody Response to Booster Dose of Diphtheria and Tetanus Toxoids: Reactions in Institutionalized Adults and Non-Institutionalized Children and Young Adults

Abstract
Both the frequency and the severity of reactions were studied in noninstitutionalized young adults and in institutionalized adults after injections of purified diphtheria and tetanus toxoids (10 Lf units each per milliliter), aluminum phosphate absorbed. Another group of institutionalized adults received diphtheria toxoid (20 Lf units per milliliter) and tetanus toxoid (10 Lf units per milliliter), aluminum phosphate adsorbed, combined with pertussis vaccine (24 opacity units per milliliter). Reactions to the antigens and doses decreased in frequency and severity in the following descending order: 0.2 ml DTP, 0.5 ml DT, 0.4 ml DT, and 0.2 ml DT.

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