Efficient Conversion of Nitriles to Amides with Basic Hydrogen Peroxide in Dimethyl Sulfoxide
- 1 January 1989
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1989 (12) , 949-950
- https://doi.org/10.1055/s-1989-27441
Abstract
Nitriles 1 are efficiently transformed into N-unsubstituted amides 2 at 20°C in 5-30 mins in good yield and with high selectivity, using basic 30% hydrogen peroxide in dimethyl sulfoxide.Keywords
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