Use of Intravenous Liposoluble Contrast Material for the Examination of the Liver and Spleen in Lymphoma

Abstract
An experimental contrast material was developed that, after i.v. injection, selectively opacifies the spleen and liver on computed tomography (CT). The contrast material contains iodinated ester of poppy seed oil in an emulsified form. Clinical trials were recently initiated to test the value of this contrast agent in Hodgkin''s and non Hodgkin''s lymphomas. Two initial patients in whom lesions were found in the spleen or liver following the infusion of the experimental contrast material that were not visualized on the precontrast and urographic contrast material enhanced CT scans are presented.