Abstract
Summary: Measurements were made of the diphtheria antibodies, antibacterial and antitoxic, in the sera of the offspring of guinea pigs previously immunized with diphtheria filtrate. The data showed that diphtheria antibodies of the antibacterial sort as well as antitoxin are placentally transmittted. The proportion of found in the sera of the offspring shortly after birth was comparable to that in the sera of their respective mothers. The sera of a number of families were studied over periods of sixty or more days following the births; the data of these tests showed that the amount of antibodies originally transferred by the mother is the important factor in determining the duration of the passive immunity of the offspring.

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