Intestinal M Cells: A Pathway for Entry of Reovirus into the Host
- 24 April 1981
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 212 (4493) , 471-472
- https://doi.org/10.1126/science.6259737
Abstract
Thirty minutes after inoculation of reovirus type 1 into the intestinal lumen of the mouse, viruses were found adhering to the surface of intestinal M cells but not other epithelial cells. Within 1 hour, viruses were seen in the M cell cytoplasm and were associated with mononuclear cells in the intercellular space adjacent to the M cell. These findings suggest that M cells are the site where reovirus penetrates the intestinal epithelium.This publication has 15 references indexed in Scilit:
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