Cytochrome P-450 interactions with the 2-chloroethylnitrosoureas and procarbazine
- 9 December 1978
- Vol. 60 (9) , 989-995
- https://doi.org/10.1016/s0300-9084(78)80585-9
Abstract
No abstract availableKeywords
This publication has 14 references indexed in Scilit:
- Mechanism of action of the nitrosoureas—1Biochemical Pharmacology, 1978
- Active site specific inactivation of chymotrypsin by cyclohexyl isocyanate formed during degradation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosoureaBiochemistry, 1977
- Effects in vivo of lymphoma ascites tumors and procarbazine, alone and in combination, upon hepatic drugmetabolizing enzymes of miceBiochemical Pharmacology, 1976
- Microsomal monooxygenation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea. Synthesis and identification of cis and trans monohydroxylated productsBiochemistry, 1975
- Alkylation and carbamoylation intermediates from the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl -1-nitrosourea (CCNU)Life Sciences, 1975
- Decomposition of BCNU (1,3-Bis(2-chloroethyl)-1-nitrosourea) in aqueous solutionBiochemical and Biophysical Research Communications, 1974
- Further evidence on the nature of microsomal metabolism of procarbazine11Procarbazine, a registered trade name by Hoffman-LaRoche, Nutley, New Jersey. and related alkylhydrazinesArchives of Biochemistry and Biophysics, 1970
- Oxidation of p-(N1-methylhydrazino methyl) -N-isopropyl benzamide (procarbazine) to the methylazo derivative and oxidative cleavage of the N2-C bond in the isolated perfused rat liverBiochemical Pharmacology, 1969
- Evidence for the hepatic metabolism of some monoalkylhydrazinesArchives of Biochemistry and Biophysics, 1969
- Methane formation in vivo from N-isopropyl α(2-methylhydrazino)-ρ-toluamide hydrochloride, a tumor-inhibiting methylhydrazine derivativeBiochemical Pharmacology, 1967