Sulfoxide Reduction in Relation to Organophosphorus Insecticide Detoxification
- 16 January 1976
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 191 (4223) , 187-188
- https://doi.org/10.1126/science.1246606
Abstract
Carbophenothion sulfoxide, an oxidative metabolite of carbophenothion, is reduced to carbophenothion in the living rat and by an in vitro system containing rat liver enzyme, reduced nicotinamide adenine dinucleotide phosphate, and flavin adenine dinucleotide phosphate. Reduction of sulfoxides, formed metabolically from certain commercial organophosphorus insecticides, may be important in ameliorating the toxicity of these compounds.Keywords
This publication has 3 references indexed in Scilit:
- Metabolic fate of bis(3,5-dichloro-2-hydroxyphenyl)-sulfoxide (bithionol sulfoxide)Biochemical Pharmacology, 1970
- Persistence, Degradation, and Bioactivity of Phorate and its Oxidative Analogues in Soil1Journal of Economic Entomology, 1970
- Reduction of Dimethylsulfoxide to Dimethylsulfide in the CatScience, 1964