Acquisition of a Specific and Potent PTP1B Inhibitor from a Novel Combinatorial Library and Screening Procedure

This publication has 52 references indexed in Scilit:

• Identification of Protein-tyrosine Phosphatase 1B as the Major Tyrosine Phosphatase Activity Capable of Dephosphorylating and Activating c-Src in Several Human Breast Cancer Cell Lines
  Journal of Biological Chemistry, 2000
• Thermodynamic Study of Ligand Binding to Protein-tyrosine Phosphatase 1B and Its Substrate-trapping Mutants
  Journal of Biological Chemistry, 2000
• Acquisition of High-Affinity, SH2-Targeted Ligands via a Spatially Focused Library
  Journal of Medicinal Chemistry, 1999
• Protein-Tyrosine Phosphatases: Biological Function, Structural Characteristics, and Mechanism of Catalysis
  Critical Reviews in Biochemistry and Molecular Biology, 1998
• The Single Sulfur to Oxygen Substitution in the Active Site Nucleophile of the Yersinia Protein-Tyrosine Phosphatase Leads to Substantial Structural and Functional Perturbations
  Biochemistry, 1997
• Probing the Function of Asp128 in the Low Molecular Weight Protein-Tyrosine Phosphatase-Catalyzed Reaction. A Pre-Steady-State and Steady-State Kinetic Investigation
  Biochemistry, 1996
• Transition state and rate-limiting step of the reaction catalyzed by the human dual-specificity phosphatase, VHR
  Biochemistry, 1995
• Why Is Phosphonodifluoromethyl Phenylalanine a More Potent Inhibitory Moiety Than Phosphonomethyl Phenylalanine Toward Protein-Tyrosine Phosphatases
  Biochemical and Biophysical Research Communications, 1995
• Potent Inhibition of Insulin Receptor Dephosphorylation by a Hexamer Peptide Containing the Phosphotyrosyl Mimetic F2Pmp
  Biochemical and Biophysical Research Communications, 1994
• Expression of a protein tyrosine phosphatase in normal and v-src-transformed mouse 3T3 fibroblasts
  The Journal of cell biology, 1992