EVIDENCE OF HYPERINSULINEMIA AND HYPOXEMIA IN THE CORD BLOOD OF NEONATES BORN TO MOTHERS WITH GESTATIONAL DIABETES

  • 1 January 1985
    • journal article
    • research article
    • Vol. 67  (3) , 81-84
Abstract
Increased cord blood C-peptide levels in neonates born to mothers with gestational diabetes (GD) were directly correlated with the increased relative birth weight ratio (BWR) of these neonates. The percentage O2 saturation of the cord blood was inversely correlated with cord blood C-peptide levels and with the relative BWR. These correlations were absent in neonates delivered to normal mothers. The results indicate the presence of both hyperinsulinemia and mild hypoxemia in neonates of mothers with GD. In poorly controlled diabetic pregnancy this hypoxemia may constitute an important fetal risk factor.

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