Conformational adaptation of nuclear receptor ligand binding domains to agonists: Potential for novel approaches to ligand design
- 28 February 2005
- journal article
- review article
- Published by Elsevier in The Journal of Steroid Biochemistry and Molecular Biology
- Vol. 93 (2-5) , 127-137
- https://doi.org/10.1016/j.jsbmb.2005.01.004
Abstract
No abstract availableKeywords
This publication has 61 references indexed in Scilit:
- Thyroxine-Thyroid Hormone Receptor InteractionsJournal of Biological Chemistry, 2004
- Selective activation of thyroid hormone signaling pathways by GC-1: a new approach to controlling cholesterol and body weightTrends in Endocrinology & Metabolism, 2004
- Ligand-Induced Changes in Estrogen Receptor Conformation As Measured by Site-Directed Spin LabelingBiochemistry, 2004
- Definition of the Surface in the Thyroid Hormone Receptor Ligand Binding Domain for Association as Homodimers and Heterodimers with Retinoid X ReceptorPublished by Elsevier ,2001
- PPARγ and the Treatment of Insulin ResistanceTrends in Endocrinology & Metabolism, 2000
- Ligand-induced stabilization of PPARγ monitored by NMR spectroscopy: implications for nuclear receptor activationJournal of Molecular Biology, 2000
- Molecular determinants of nuclear receptor-corepressor interactionGenes & Development, 1999
- Retinoic acid receptor: a simulation analysis of retinoic acid binding and the resulting conformational changesJournal of Molecular Biology, 1999
- A Novel TR Mutation (R383H) in Resistance to Thyroid Hormone Syndrome Predominantly Impairs Corepressor Release and Negative Transcriptional RegulationMolecular Endocrinology, 1998
- Glucocorticoids in malignant lymphoid cells: Gene regulation and the minimum receptor fragment for lysisThe Journal of Steroid Biochemistry and Molecular Biology, 1992