Rapid Loss of Oct-4 and Pluripotency in Cultured Rodent Blastocysts and Derivative Cell Lines1
Open Access
- 1 January 2003
- journal article
- Published by Oxford University Press (OUP) in Biology of Reproduction
- Vol. 68 (1) , 222-229
- https://doi.org/10.1095/biolreprod.102.006197
Abstract
The POU transcription factor Oct-4 is essential for the pluripotent character of the mouse inner cell mass (ICM) and derivative embryonic stem (ES) cKeywords
This publication has 34 references indexed in Scilit:
- Oct‐4 : Gatekeeper in the Beginnings of Mammalian DevelopmentThe International Journal of Cell Cloning, 2001
- Molecular Mechanism to Maintain Stem Cell Renewal of ES Cells.Cell Structure and Function, 2001
- Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cellsNature Genetics, 2000
- In line with our ancestors: Oct-4 and the mammalian germBioEssays, 1998
- Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4Cell, 1998
- The origin and efficient derivation of embryonic stem cells in the mouseProceedings of the National Academy of Sciences, 1997
- A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryoNature, 1990
- A novel octamer binding transcription factor is differentially expressed in mouse embryonic cellsCell, 1990
- Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells.Proceedings of the National Academy of Sciences, 1981
- Establishment in culture of pluripotential cells from mouse embryosNature, 1981