FAILLURE TO DETECT 3β,11β,17α,21-TETRAHYDROXY-5-PREGNEN-20-ONE IN PLASMA OBTAINED FROM HUMAN UMBILICAL CORDS AND HUMAN INFANT URINE

1 July 1971

journal article
Published by Oxford University Press (OUP) in Acta Endocrinologica

Vol. 67 (3) , 531-534
https://doi.org/10.1530/acta.0.0670531

Abstract

A possible pathway for the synthesis of cortisol in utero and in early infancy, via Δ⁵ steroidal intermediates has been suggested by the tentative identification of hydroxylated derivatives of 3β-hydroxy-5-pregnen-20-one. The penultimate compound in such a pathway (3β,11β,17α,21-tetrahydroxy-5-pregnen-20-one) has been searched for in blood from umbilical cords and in infant urine. None could be detected at a level of 0.5 μg/100 ml.

Keywords

TETRAHYDROXY
11Β
17Α
PREGNEN
INFANT URINE
UMBILICAL CORDS

This publication has 0 references indexed in Scilit: