Transient Anuria Following Administration of Angiotensin I-Converting Enzyme Inhibitor (SQ 14225) in a Patient with Renal Artery Stenosis of the Solitary Kidney Successfully Treated with Renal Autotransplantation

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Abstract
A patient is reported with renal artery stenosis who had only 1 kidney and in whom acute renal impairment developed with transient anuria after the administration of captopril. Although inhibition of the angiotensin-converting enzyme is considered efficient treatment for hypertension associated with chronic renal failure, care should be taken when captopril is administered initially to a patient with decreased renal function, under the conditions of Na and water depletion. The renovascular hypertension in this patient was treated successfully by renal autotransplantation.