Cholangiocarcinoma with a Background of Hepatitis B Virus-associated Cirrhosis.
- 1 January 2001
- journal article
- case report
- Published by Japanese Society of Internal Medicine in Internal Medicine
- Vol. 40 (5) , 382-385
- https://doi.org/10.2169/internalmedicine.40.382
Abstract
Recently, hepatitis virus-associated chronic hepatitis or cirrhosis has been suggested to be involved in the pathogenesis of Cholangiocarcinoma (CC). A 52-year-old man was diagnosed as CC with a background of hepatitis B virus (HBV)-dependent cirrhosis. A minute hepatic tumor was found during the follow-up, and was diagnosed as CC on percutaneous biopsy. The patient died of hepatic failure and an autopsy revealed the tumor to be a well to moderately differentiated adenocarcinoma. An immunohistological analysis of HBV X gene-encoded protein (HBX) was neither detected in the cancerous nor in the noncancerous tissue. No oncogenic role of the virus was verified in this case.(Internal Medicine 40: 382-385, 2001)Keywords
This publication has 0 references indexed in Scilit: