N-oxide as a potential function in the design of enzyme inhibitors. Application to 2,3-epoxysqualene-sterol cyclases
- 1 January 1985
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 15,p. 1054-1055
- https://doi.org/10.1039/c39850001054
Abstract
The N-oxides of several tertiary amines possessing an aliphatic long chain are more potent inhibitors of 2,3-epoxysqualene-β-amyrin and -lanosterol cyclases than their parent amines.Keywords
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