A simple route to α-aminoketones and related derivatives by dianion acylation reactions; an improved preparation of δ-aminolevulinic acid
- 1 January 1978
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 17,p. 753-754
- https://doi.org/10.1039/c39780000753
Abstract
Acylation of the dianion (1) derived from ethyl hippurate (2) using anhydrides, followed by acid hydrolysis, provides a general route to α-aminoketones; a short and convenient preparation of the porphyrin precursor δ-aminolevulinic acid (as the hydrochloride) by the foregoing procedure is described.Keywords
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