The central nervous system pathology in multiple neurofibromatosis

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Abstract
Nine unselected patients suffering from neurofibromatosis were subjected to detailed autopsy studies. An unusually high incidence of cerebral tumors, many clinically latent, was found. Vascular lesions were found in 3 patients, a feature not previously emphasized in this disease. The incidence and nature of the cranial lesions and their pathology, clinical significance, and possible embryological implications are discussed.