Graft-vs-host reaction in skin: histological immunological and ultrastructural studies
Open Access
- 1 January 1979
- journal article
- research article
- Published by Medical Journals Sweden AB in Acta Dermato-Venereologica
- Vol. 59 (1) , 7-13
- https://doi.org/10.2340/0001555559713
Abstract
A case of graft-vs-host reaction after bone marrow transplantation is described. Histopathologic and ultrastructural findings in involved skin showed necrotic keratinocytes and abnormal melanocytes with satellite lymphocytes. No deposits of immunoglobulins or complement were found. These data provide direct evidence that chronic graft-vs-host disease in humans may be related to cellular hypersensitivity rather than to serum factors.This publication has 2 references indexed in Scilit:
- SKIN BIOPSY IN DIAGNOSIS OF ACUTE GRAFT VERSUS HOST DISEASE IN MAN1977
- Immunoglobulins and Complement in Skin in Graft-Versus-Host DiseaseAnnals of Internal Medicine, 1976