The nonpeptide NK-1 receptor antagonists LY303870 and LY306740 block the responses of spinal dorsal horn neurons to substance P and to peripheral noxious stimuli
- 1 January 1998
- journal article
- Published by Elsevier in Neuroscience
- Vol. 83 (4) , 1251-1260
- https://doi.org/10.1016/s0306-4522(97)00313-8
Abstract
No abstract availableKeywords
This publication has 43 references indexed in Scilit:
- [3H]LY303870, a Novel Nonpeptide Radioligand for the NK‐1 ReceptorJournal of Neurochemistry, 1996
- Synthesis of RPR 100893, prototype of a new series of potent and selective non peptide NK1 antagonists : the triarylperhydroisoindolols.Bioorganic & Medicinal Chemistry Letters, 1994
- Perhydrothiopyranopyrroles derivatives : A novel series of potent and selective nonpeptide NK1 antagonists.Bioorganic & Medicinal Chemistry Letters, 1994
- Tachykinin receptors and tachykinin receptor antagonistsJournal of Autonomic Pharmacology, 1993
- Enhancement of spinothalamic neuron responses to chemical and mechanical stimuli following combined micro-iontophoretic application of n-methyl-d-aspartic acid and substance PPain, 1991
- NMDA receptor antagonist blocks the facilitation of the tail flick reflex in the rat induced by intrathecal administration of substance P and by noxious cutaneous stimulationNeuroscience Letters, 1991
- A Potent Nonpeptide Antagonist of the Substance P (NK 1 ) ReceptorScience, 1991
- On the Role of Galanin, Substance P and Other Neuropeptides in Primary Sensory Neurons of the Rat: Studies on Spinal Reflex Excitability and Peripheral AxotomyEuropean Journal of Neuroscience, 1990
- Interactions between substance P, calcitonin gene-related peptide, taurine and excitatory amino acids in the spinal cordPain, 1990
- Substance P: localization in synaptic vesicles in rat central nervous systemJournal of Neurochemistry, 1977