Platelet monoamine oxidase activity in schlzophrenic families-kinetic aspects
- 23 April 2008
- journal article
- Published by Wiley in Clinical Genetics
- Vol. 19 (5) , 405-409
- https://doi.org/10.1111/j.1399-0004.1981.tb00735.x
Abstract
Monoamine oxidase activity (MAO) was determined in platelets in samples from a North-Swedish pedigree with a high frequency of schizophrenia. The MAO assay was performed with phenethylamine as substrate and with two concentrations of oxygen (0.06 and 0.12 mM). A tendency to lowered Vmax and increased apparent Km values was observed among the schizophrenic subjects, although there were no statistically significant differences in apparent Km and Vmax values between schizophrenics and their non-schizophrenic relatives.Keywords
This publication has 22 references indexed in Scilit:
- Platelet MAO Vmax and Km in chronic schizophrenic subjectsAmerican Journal of Psychiatry, 1980
- The interaction between human platelet monoamine oxidase, its monoamine substrates and oxygenBiochemical Pharmacology, 1979
- Platelet monoamine oxidase in a pedigree with schizophrenia: an interlaboratory projectClinical Genetics, 1979
- Schizophrenia in a North Swedish geographical isolate, 1900–1977. Epidemiology, genetics and biochemistryClinical Genetics, 1978
- Activities of Types A and B MAO and Catechol-O-methyltransferase in Blood Cells and Skin Fibroblasts of Normal and Chronic Schizophrenic SubjectsArchives of General Psychiatry, 1978
- Decreased Platelet Monoamine Oxidase Activity in Chronic Schizophrenia, Shown With Novel SubstratesArchives of General Psychiatry, 1978
- PLATELET MONOAMINE OXIDASE IN SCHIZOPHRENIAThe Lancet, 1977
- Platelet monoamine oxidase in chronic schizophreniaAmerican Journal of Psychiatry, 1977
- Platelet serotonin concentration and monoamine oxidase activity in unmedicated chronic schizophrenic and in schizoaffective patientsPsychological Medicine, 1977
- Decreased blood platelet MAO activity in unmedicated chronic schizophrenic patientsAmerican Journal of Psychiatry, 1976