SAFFLOWER OIL AND PLASMA CHOLESTEROL

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Abstract
To the Editor:— A paper by Perkins, Wright, and Gatje in the April 26, 1958, issue ofThe Journal, page 2132, presents data which indicate that the addition of safflower oil to an average American diet produces no depression of plasma cholesterol level. The authors estimated that the final ratio of unsaturated to saturated fat in the diet was about one to two. The absolute amount of safflower oil was slightly less than 50 Gm. The safflower emulsion was added without any reduction in the diet calories, i.e., the total caloric intake was increased by something more than 400 calories per day. This paper is timely, inasmuch as one cannot overemphasize the fact that, if lowering of the plasma cholesterol level is to be achieved by the use of polyunsaturated fats, it is necessary to modify the entire diet. This is brought out to some degree in a recent paper

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