EGF regulates plasminogen activator inhibitor‐1 (PAI‐1) by a pathway involving c‐Src, PKCδ, and sphingosine kinase 1 in glioblastoma cells
Open Access
- 12 September 2007
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 22 (2) , 455-465
- https://doi.org/10.1096/fj.07-8276com
Abstract
Patients with gliomas expressing high levels of epidermal growth factor receptor (EGFR) and plasminogen activator inhibitor‐1 (PAI‐1) have a shorter overall survival prognosis. Moreover, EGF enhances...Keywords
Funding Information
- National Institutes of Health (NSO44118, NSO46280)
- National Institute of Mental Health (R01 CA61774)
- National Institutes of Health (P30 CA16059)
- National Institute of Mental Health
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