Brain Volume and Cerebrospinal Fluid Pressure During Hypothermia

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Abstract
As compared to normothermic controls, the brain volume of the anesthetized dog decreases 4% at 25[degree]C; while the extracerebral space, meaning that intracranial space not occupied by brain, increases 32%. Cerebrospinal fluid pressure decreases progressively with reduction of temperature at 5.6% of the pre-cooling value per degree centigrade between 37[degree] and 25[degree]. Venous pressure also decreases as a function of temperature, at 5.4% of the pre-cooling value per degree centigrade between 37[degree] and 25[degree].

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