The role of trace elements and phosphates in the synthesis of vascular-permeability factor by Vibrio cholerae
- 1 August 1981
- journal article
- research article
- Published by Microbiology Society in Journal of Medical Microbiology
- Vol. 14 (3) , 243-250
- https://doi.org/10.1099/00222615-14-3-243
Abstract
Trace element and phosphate requirements for the synthesis of vascular-permeability factor (PF) by V. cholerae strains B1307 and VC12 were investigated. While Mg appeared to be indispensable for strain VC12, small amounts of PF were synthesized by strain B1307 in the presence of Fe, Zn and Mn. Even in the latter strain, maximum synthesis was recorded only in Mg containing media. Phosphates in the range 0.75-6.00 mM controlled the synthesis of PF by both strains.This publication has 5 references indexed in Scilit:
- EFFECT OF METAL-IONS ON THE PRODUCTION OF VASCULAR-PERMEABILITY FACTOR BY 569B STRAIN OF VIBRIO CHOLERAE1979
- Phosphate inhibition of secondary metabolism in Serratia marcescensApplied and Environmental Microbiology, 1977
- Biosynthesis of Secondary Metabolites: Roles of Trace MetalsPublished by Elsevier ,1969
- In Vitro Production of Choleragen and Vascular Permeability Factor byVibrio choleraeJournal of Bacteriology, 1968
- A Permeability Factor (Toxin) Found in Cholera Stools and Culture Filtrates and its Neutralization by Convalescent Cholera SeraNature, 1965