A Convenient Synthesis of 5-Alkylbicyclo[3.1.0]hexan-2-ones Including the Natural Product Sabina Ketone

1 January 1987

journal article
research article
Published by CSIRO Publishing in Australian Journal of Chemistry

Vol. 40 (7) , 1321-1325
https://doi.org/10.1071/ch9871321

Abstract

Simple 5-alkylbicyclo[3.1.0]hexan-2-ones, including the natural product sabina ketone, can be prepared in four steps from aromatic ethers via Birch reduction, hydrogen chloride addition, hydrolysis and then base treatment of the resultant 4-chlorocyclohexanones.

Keywords

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