Determination of AL01576 Concentration in Rat Lenses and Plasma by Bioassay for Aldose Reductase Activity Measurements

1 January 1989

journal article
research article
Published by S. Karger AG in Ophthalmic Research

Vol. 21 (4) , 285-291
https://doi.org/10.1159/000266871

Abstract

Investigations on the disposition of the highly effective aldose reductase inhibitor ALO 1576 were carried out in pigmented rats after oral dosing and topical administration of a 0.1 % ophthalmic susp

Keywords

ALO15 76
PHARMACOKINETICS
ALDOSE REDUCTASE INHIBITOR
DRUG CONCENTRATION
RAT
PLASMA
LENS
DRUG DISTRIBUTION
TOPICAL APPLICATION
ORAL ADMINISTRATION

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