Metabolic Profiling of Urinary Organic Acids by Single and Multicolumn Capillary Gas Chromatography
- 1 January 1989
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Chromatographic Science
- Vol. 27 (1) , 23-29
- https://doi.org/10.1093/chromsci/27.1.23
Abstract
High-resolution gas chromatography (HRGC) and gas chromatography/mass spectrometry (GC/MS) are the techniques of choice to determine the retention indices of more than 200 organic acids as their trimethylsilyl (TMS) or oxime-trimethylsilyl derivatives. Several types of apolar and semipolar fused-silica capillary columns (OV-1, SE-52, and OV-1701), used to analyze and separate organic acids isolated from urine samples, are evaluated.Keywords
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