"Microsome" Fraction of Brain: Structural Changes Induced by Ascorbic Acid
- 16 August 1963
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 141 (3581) , 628-630
- https://doi.org/10.1126/science.141.3581.628
Abstract
The usual vesicular configuration of membrane fragments in the brain "microsome" fraction is radically altered by treatment with ascorbic acid and adenosine monophosphate. Lightscattering measurements and electron micrographs show that the treated membranes assume predominantly planar forms. This change in structure appears to be contingent upon a continued transport of electrons from ascorbic acid.Keywords
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