A Novel Microwave-Activated Sonogashira Coupling Reaction and Cleavage using Polyethylene Glycol as Phase-Transfer Catalyst and Polymer Support
- 1 April 2002
- journal article
- research article
- Published by SAGE Publications in Journal of Chemical Research
- Vol. 2002 (4) , 173-175
- https://doi.org/10.3184/030823402103171564
Abstract
Under microwave-activation polyethylene glycol bound 4-iodobenzoic acid could be readily reacted with various terminal alkynes in excellent yields and purity using polyethylene glycol (PEG) as a solid-liquid phase-transfer catalyst and polymer support; the cleavage could be dramatically accelerated under microwave activation.Keywords
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